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Vurderingen tager udover risikoen for forgiftning blandt andet også udgangspunkt i "stoffets afhængighedsskabende potentiale" og "risiko for anden sygdom eller skadevirkning som fileølge af brug af stoffet".Generelt har medicin fra den tricykliske gruppe af antidepressiva større smertestillende effekt ved lavere dosis close SNRI præparater, me